Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-BRD9500
BRD9500

Chemical Structure : BRD9500

CAS No.: 1630760-75-6

BRD9500

Catalog No.: PC-25668Not For Human Use, Lab Use Only.

BRD9500 is a potent, selective and orally active phosphodiesterases 3 (PDE3) inhibitor with IC50 of 10 and 27 nM for PDE3A and PDE3B, respectively.

Packing Price Stock Quantity
5 mg $218 In stock
10 mg $358 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BRD9500 is a potent, selective and orally active phosphodiesterases 3 (PDE3) inhibitor with IC50 of 10 and 27 nM for PDE3A and PDE3B, respectively.
BRD9500 is potent against biomarker-positive HeLa and SK-MEL-3 cells, selective for PDE3 in a PDE panel, clean in a CYP panel, hERG assay, and Ames test, and active in a murine model of melanoma.

Physicochemical Properties

M.Wt 291.33
Formula C15H18FN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-6-(3-fluoro-4-morpholinophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

References

1. Lewis TA, et al. ACS Med Chem Lett. 2024 Sep 10;15(10):1662-1667.

2. Lewis T. A. et al. ACS Med. Chem. Lett. 2019, 10, 1537–1542.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: