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BS148

Chemical Structure : BS148

CAS No.: 2162116-09-6

BS148 (BS-148)

Catalog No.: PC-35305Not For Human Use, Lab Use Only.

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.
BS148 specifically inhibits the growth of metastatic malignant melanoma cell lines without affecting normal human melanocytes.

Physicochemical Properties

M.Wt 361.606
Formula C21H31NS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(1,4-dithiaspiro[4.5]decan-2-ylmethyl)-4-benzylpiperidine

References

1. Franchini S, et al. ChemMedChem. 2017 Nov 22;12(22):1893-1905.

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