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Chemical Structure : BT-13
CAS No.: 924537-98-4
Catalog No.: PC-61589Not For Human Use, Lab Use Only.
RET agonist BT13 is a novel small molecule GDNF receptor RET agonist, potently and selectively activates RET and its downstream intracellular signaling cascades in immortalized cells (EC50~20 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $218 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $698 | In stock | |
| 100 mg | $1180 | In stock | |
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| 1 g | Get quote |
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RET agonist BT13 (BT-13) is a novel small molecule GDNF receptor RET agonist, potently and selectively activates RET and its downstream intracellular signaling cascades in immortalized cells (EC50~20 uM)>
RET agonist BT13 promotes neurite outgrowth from cultured dorsal root ganglia (DRG) sensory neurons in vitro.
RET agonist BT13 alleviates mechanical hypersensitivity and reverses injury-induced changes in protein expression in DRG neurons in rat model of neuropathic pain.
| M.Wt | 517.54 | |
| Formula | C23H27F4N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N,N-diethyl-3-(4-(4-fluoro-2-(trifluoromethyl)benzoyl)piperazin-1-yl)-4-methoxybenzenesulfonamide |
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1. Sidorova YA, et al. Front Pharmacol. 2017 Jun 21;8:365.
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