BTKi-2 | BTK inhibitor | Probechem Biochemicals

Chemical Structure : BTKi-2

CAS No.: 1558036-85-3

BTKi-2 (BTK inhibitor-2, Btk inhibitor 2)

Catalog No.: PC-27129Not For Human Use, Lab Use Only.

BTKi-2 (Btk inhibitor 2) is a highly potent BTK inhibitor with IC50 of 0.18 nM, also exhibits IC50 of 535 nM against vaccinia virus (VACV) and 260 nM against MPXV in vitro.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$148	In stock
50 mg	$248	In stock
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Biological Activity

BTKi-2 (Btk inhibitor 2) is a highly potent BTK inhibitor with IC50 of 0.18 nM, also exhibits IC50 of 535 nM against vaccinia virus (VACV) and 260 nM against MPXV in vitro.

Physicochemical Properties

M.Wt	431.50
Formula	C24H25N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-1-(1-acryloylpiperidin-3-yl)-5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide

References

1. Mark E Schnute, et al. ACS Med Chem Lett. 2018 Dec 3;10(1):80-85.

2. Chen Yang, et al. Virol Sin. 2026 Jun 19:S1995-820X(26)00100-8.

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BTKi-2 (BTK inhibitor-2, Btk inhibitor 2)

Biological Activity

Physicochemical Properties

References

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