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BVT173187

Chemical Structure : BVT173187

CAS No.: 1374984-75-4

BVT173187 (BVT 173187)

Catalog No.: PC-20394Not For Human Use, Lab Use Only.

BVT173187 is a potent, selective, non-peptide inhibitor of formyl peptide receptor 1 (FPR1), inhibits fMLF and WKYMVM induced oxidase activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BVT173187 is a potent, selective, non-peptide inhibitor of formyl peptide receptor 1 (FPR1), inhibits fMLF and WKYMVM induced oxidase activity.
BVT173187 also affects signaling through the C5aR and CXCR (recognizing IL8).

Physicochemical Properties

M.Wt 330.59
Formula C14H10Cl3NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,5-dichloro-N-(2-chloro-5-methyl-phenyl)-2-hydroxy-benzamide

References

1. Hülya Cevik-Aras, et al. Biochem Pharmacol. 2012 Jun 15;83(12):1655-62.

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