Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : BX-912
CAS No.: 702674-56-4
Catalog No.: PC-42781Not For Human Use, Lab Use Only.
BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 25 mg | $288 | In stock | |
| 100 mg | $748 | In stock | |
| 500 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BX-912 (BX912) is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 26 nM; blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis.
| M.Wt | 471.3536 | |
| Formula | C20H23BrN8O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-Pyrrolidinecarboxamide, N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]- |
|
1. Feldman RI, et al. J Biol Chem. 2005 May 20;280(20):19867-74.
2. Mashukova A, et al. Mol Biol Cell. 2012 May;23(9):1664-74.
3. Sturm EM, et al. Eur J Immunol. 2015 May;45(5):1548-59.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
