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Baicalein

Chemical Structure : Baicalein

CAS No.: 491-67-8

Baicalein (5,6,7-Trihydroxyflavone)

Catalog No.: PC-24501Not For Human Use, Lab Use Only.

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase (XO, xanthine oxidoreductase) inhibitor with IC50 of 3.12 uM, also is a noncovalent, nonpeptidomimetic inhibitor of SARS-CoV-2 3CLpro with potent antiviral activities, prevents cancer progression by inducing apoptosis, autophagy and genome instability.

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250 mg $98 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase (XO, xanthine oxidoreductase) inhibitor with IC50 of 3.12 uM, also is a noncovalent, nonpeptidomimetic inhibitor of SARS-CoV-2 3CLpro with potent antiviral activities, prevents cancer progression by inducing apoptosis, autophagy and genome instability.

Physicochemical Properties

M.Wt 270.24
Formula C15H10O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5,6,7-Trihydroxyflavone

References

1. Shieh DE,et al. Anticancer Res. 2000 Sep-Oct;20(5A):2861-5.

2. Song J, et al. Biochem Pharmacol. 2021 Jan;183:114302.

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