Bamocaftor | CFTR corrector | Probechem Biochemicals

Chemical Structure : Bamocaftor

Catalog No.: PC-72975Not For Human Use, Lab Use Only.

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.

M.Wt	591.65
Formula	C28H32F3N5O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(Phenylsulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]-1H-pyrazol-1-yl]-2-[(4S)-2,2,4-trimethyl-1-pyrrolidinyl]-3-pyridinecarboxamid

1. Davies JC, et al. N Engl J Med. 2018 Oct 25;379(17):1599-1611.

2. Taylor-Cousar JL, et al. ERJ Open Res. 2019 Jun 17;5(2):00082-2019.