You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-GABA Receptor-Basmisanil
Basmisanil

Chemical Structure : Basmisanil

CAS No.: 1159600-41-5

Basmisanil (RG-1662;RO5-186582)

Catalog No.: PC-45060Not For Human Use, Lab Use Only.

A novel selective negative allosteric modulator of the GABAA receptor α5-subtype, which is under development for the treatment of cognitive impairment associated with Down syndrome..

Packing Price Stock Quantity
5 mg $280 In stock
10 mg $440 In stock
25 mg $880 In stock
50 mg $1280 In stock

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A novel selective negative allosteric modulator of the GABAA receptor α5-subtype, which is under development for the treatment of cognitive impairment associated with Down syndrome.

Schizophrenia

Phase 2 Clinical

Physicochemical Properties

M.Wt 445.464
Formula C21H20FN3O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 32 mg/mL

Chemical Name/SMILES

Methanone, (1,1-dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]-

References

1. Myers JF, et al. J Cereb Blood Flow Metab. 2017 Jun;37(6):2137-2148.

2. Costa AC, et al. CNS Drugs. 2013 Sep;27(9):679-702.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: