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Bavachalcone

Chemical Structure : Bavachalcone

CAS No.: 28448-85-3

Bavachalcone (Broussochalcone B)

Catalog No.: PC-25628Not For Human Use, Lab Use Only.

Bavachalcone is a potent apoptosis induce, exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells, also acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway, also targets transferrin receptor (TFRC) and sensitizes gemcitabine to affect bladder cancer progression.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bavachalcone is a potent apoptosis inducer, exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells, also acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway, also targets transferrin receptor (TFRC) and sensitizes gemcitabine to affect bladder cancer progression.

Physicochemical Properties

M.Wt 324.38
Formula C20H20O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-1-(2,4-Dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

References

1. Zihao Zhang, et al. Imeta. 2025 Aug 17;4(5):e70071.

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