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Chemical Structure : Bay K-8644
CAS No.: 71145-03-4
Catalog No.: PC-62070Not For Human Use, Lab Use Only.
Bay K-8644 is a potent L-type calcium channels (LTCCs) activator with EC50 of 17.3 nM, has positive inotropic, vasoconstrictive and behavioral effects in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $158 | In stock | |
| 25 mg | $248 | In stock | |
| 50 mg | $378 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote |
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Bay K-8644 is a potent L-type calcium channels (LTCCs) activator with EC50 of 17.3 nM, has positive inotropic, vasoconstrictive and behavioral effects in vivo.
Bay K-8644 enables reprogramming of Oct4/Klf4-transduced mouse embryonic fibroblasts (MEFs) to induce pluripotent stem cells (iPSCs) combination with BIX-01294.
| M.Wt | 356.3 | |
| Formula | C16H15F3N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester |
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1. Wang W, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32.
2. Greenberg DA, et al. Brain Res. 1984 Jul 9;305(2):365-8.
3. Bourson A, et al. Eur J Pharmacol. 1989 Feb 7;160(3):339-47.
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