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Bedaquiline fumarate

Chemical Structure : Bedaquiline fumarate

CAS No.: 845533-86-0

Bedaquiline fumarate (R403323;TMC207 fumarate;R207910 fumarate)

Catalog No.: PC-63299Not For Human Use, Lab Use Only.

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Bacterial Infection

Approved

Physicochemical Properties

M.Wt 671.588
Formula C36H35BrN2O6
CAS No. 845533-86-0
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name

(1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid

References

1. Jang JC, et al. J Microbiol. 2017 Apr 20.

2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).

3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.

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