Catalog No.: PC-27657Not For Human Use, Lab Use Only.
Bergamottin (5-Geranoxypsoralen, Bergamotine) is a bioactive component of bergamot and a competitive inhibitor of cytochrome P450 1A1 (CYP1A1) with Ki of 10.7 nM.
Bergamottin (5-Geranoxypsoralen, Bergamotine) is a bioactive component of bergamot and a competitive inhibitor of cytochrome P450 1A1 (CYP1A1) with Ki of 10.7 nM.
Bergamottin ameliorates the progression of osteoarthritis via the Sirt1/NF-kappaB pathway.
Bergamottin inhibits porcine reproductive and respiratory syndrome virus (PRRSV), blocks expression of the non-structural proteins (Nsps), leading to the interruption of replication and transcription complex (RTC) formation and viral dsRNA synthesis.
Bergamottin exhibits inhibitory activity against SARS-CoV-2 in vitro, ex vivo, and in vivo, interferes with multiple stages of virus life cycles, specifically blocking the SARS-CoV-2 spike-mediated membrane fusion and effectively reducing viral RNA synthesis.
