Bevacizumab |CAS:216974-75-3 Probechem Biochemicals

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Chemical Structure : Bevacizumab

CAS No.:

Bevacizumab (Anti-human VEGF mAb, human IgG1-Kappa)

Catalog No.: PC-Ab1010Not For Human Use, Lab Use Only.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, inhibits its interaction with VEGFR-1 and VEGFR-2. Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with EC50 of 0.047 ug/ml; induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

Physicochemical Properties

M.Wt
Formula	Human IgG1-Kappa
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

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Bevacizumab (Anti-human VEGF mAb, human IgG1-Kappa)

Biological Activity

Physicochemical Properties

References

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