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Bithionol

Chemical Structure : Bithionol

CAS No.: 97-18-7

Bithionol

Catalog No.: PC-45376Not For Human Use, Lab Use Only.

An anthelmintic that has antibacterial and anthelmintic properties along with algaecide activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

An anthelmintic that has antibacterial and anthelmintic properties along with algaecide activity; has been shown to be a potent inhibitor of soluble adenylyl cyclase (sAC) with IC50 of 4.0 uM; also blocks pathogenicity of bacterial toxins, ricin, and Zika virus; causes dose dependent cytotoxicity against ovarian cancer cell lines with IC50 of 19-60 uM.

Physicochemical Properties

M.Wt 356.0518
Formula C12H6Cl4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

Phenol, 2,2'-thiobis[4,6-dichloro-

References

1. Leonardi W, et al. Sci Rep. 2016 Sep 30;6:34475.

2. Kleinboelting S, et al. J Biol Chem. 2016 Apr 29;291(18):9776-84.

3. Ayyagari VN, et al. BMC Cancer. 2014 Feb 4;14:61.

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