Bivamelagon | MC4R agonist | Probechem Biochemicals

Chemical Structure : Bivamelagon

Bivamelagon (LB54640, LB-54640)

Catalog No.: PC-26948Not For Human Use, Lab Use Only.

Bivamelagon (LB54640) is a potent, selective, next-generation oral melanocortin receptor 4 (MC4R) agonist with EC50 of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay).

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Biological Activity

Bivamelagon (LB54640) is a potent, selective, next-generation oral melanocortin receptor 4 (MC4R) agonist with EC50 of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay).

Physicochemical Properties

M.Wt	629.28
Formula	C35H53ClN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3S,5S)-1-((3S,4R)-1-(tert-butyl)-4-(4-chlorophenyl)pyrrolidine-3-carbonyl)-5-(morpholine-4-carbonyl)pyrrolidin-3-yl)-N-((1s,4R)-4-methylcyclohexyl)isobutyramide

References

1. Patent WO2021091283 A1.

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Bivamelagon (LB54640, LB-54640)

Biological Activity

Physicochemical Properties

References

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