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Chemical Structure : Bm-MPK1-IN-15b
Catalog No.: PC-63332Not For Human Use, Lab Use Only.
Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM.
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Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM; inhibits human p38α and JNK3 with IC50 of 26 and 170 nM, respectively; reduces the motility of adult worms at 100 nM, Bm-MPK1-IN-15b is a tool compound for in vivo studies aimed at strengthening the role of Bm MPK1 in B. malayi response to host oxidative stress.
| M.Wt | 391.475 | |
| Formula | C22H25N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tummalapalli SR, et al. ACS Med Chem Lett. 2018 Feb 9;9(3):210-214.
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