Catalog No.: PC-23945Not For Human Use, Lab Use Only.
Bisperoxovanadium (bpV(phen)) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=343 nM), and PTP-1β (IC50=920 nM).
Bisperoxovanadium (bpV(phen)) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=343 nM), and PTP-1β (IC50=920 nM). Bisperoxovanadium activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase.
