Chemical Structure : Brivanib
CAS No.:
649735-46-6
Brivanib
(BMS-540215, BMS540215)
Catalog No. : PC-42534Not For Human Use, Lab Use Only.
Brivanib (BMS540215) is a potent, dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4253401
Biological Activity
Brivanib (BMS-540215) is a potent, dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
Physicochemical Properties
M.Wt
370.3776
Formula
C19H19FN4O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 50 mg/mL
Chemical Name/SMILES
2-Propanol, 1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-, (2R)-
References
1. Bhide RS, et al. J Med Chem
2. Bhide RS, et al. Mol Cancer Ther.
3. Huynh H, et al. Clin Cancer Res.
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