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Chemical Structure : Brivanib alaninate
CAS No.: 649735-63-7
Catalog No.: PC-42533Not For Human Use, Lab Use Only.
A prodrug of Brivanib, which is a dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $629.6 | In stock | |
| 100 mg | $1008 | In stock |
Bulk size, bulk discount!
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A prodrug of Brivanib, which is a dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively; exhibits improved aqueous solubility and oral bioavailability of the parent compound.
Liver Cancer
Phase 3 Clinical
| M.Wt | 441.4555 | |
| Formula | C22H24FN5O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
L-Alanine, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl ester |
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1. Cai ZW, et al. J Med Chem. 2008 Mar 27;51(6):1976-80.
2. Huynh H, et al. Clin Cancer Res. 2008 Oct 1;14(19):6146-53.
3. Patel RR, et al. Eur J Cancer. 2010 Jun;46(9):1537-53.
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