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Bromoenol Lactone

Chemical Structure : Bromoenol Lactone

CAS No.: 88070-98-8

Bromoenol Lactone (HELSS)

Catalog No.: PC-26700Not For Human Use, Lab Use Only.

Bromoenol Lactone (HELSS) is a potent, irreversible, selective inhibitor of calcium-independent phospholipase A2 (iPLA2, GVIA iPLA 2, iPLA2β) inhibitor with IC50 of 1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bromoenol Lactone (HELSS) is a potent, irreversible, selective inhibitor of calcium-independent phospholipase A2 (iPLA2, GVIA iPLA 2, iPLA2β) inhibitor with IC50 of 1 uM.

Physicochemical Properties

M.Wt 317.18
Formula C16H13BrO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-6-(Bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one

References

1. Chakraborty S, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):329-40.

2. Fensome-Green A, et al. Cell Calcium. 2007 Feb;41(2):145-53.

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