Butenafine hydrochloride | squalene epoxidase

Chemical Structure : Butenafine hydrochloride

CAS No.: 101827-46-7

Butenafine hydrochloride (KP363 hydrochloride)

Catalog No.: PC-45219Not For Human Use, Lab Use Only.

A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.

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1 g	$68	In stock
5 g	$138	In stock
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Biological Activity

Butenafine (KP363) is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
Butenafine displays superior activity against Candida albicans than terbinafine and naftifine.
Butenafine demonstrates low MICs against Cryptococcus and Aspergillus.

Physicochemical Properties

M.Wt	353.9281
Formula	C23H28ClN
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1)

References

1. Singal A. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005.

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Butenafine hydrochloride (KP363 hydrochloride)

Biological Activity

Physicochemical Properties

References

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