C-021 dihydrochloride |CAS:1784252-84-1 Probechem Biochemicals

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Chemical Structure : C-021 dihydrochloride

C-021 dihydrochloride (C021 dihydrochloride)

Catalog No.: PC-61983Not For Human Use, Lab Use Only.

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.

Physicochemical Properties

M.Wt	540.57
Formula	C27H41N5O2.2HCl
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride

References

1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73.

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C-021 dihydrochloride (C021 dihydrochloride)

Biological Activity

Physicochemical Properties

References

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