C. difficile inhibitor 57

Chemical Structure : C. difficile inhibitor 57

Catalog No.: PC-21216Not For Human Use, Lab Use Only.

C. difficile inhibitor 57 is a potent, selective, narrow-spectrum antibacterial against Clostridioides difficile with MIC50 of 0.5 ug/mL, targets cell-wall synthesis.

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Biological Activity

C. difficile inhibitor 57 is a potent, selective, narrow-spectrum antibacterial against Clostridioides difficile with MIC50 of 0.5 ug/mL, targets cell-wall synthesis.
C. difficile inhibitor 57 is not active against representative gut bacteria or other Gram-positive and Gram-negative bacteria, including MRSA.

Physicochemical Properties

M.Wt	341.33
Formula	C16H15N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-(cyclopentyloxy)phenyl)-5-(4-nitro-1H-imidazol-2-yl)-1,2,4-oxadiazole

References

1. Qian Y, et al. J Med Chem. 2023 Sep 21. doi: 10.1021/acs.jmedchem.3c01249.

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