C7683 | Cbl-b inhibitor | Probechem Biochemicals

Chemical Structure : C7683

Catalog No.: PC-21555Not For Human Use, Lab Use Only.

C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.

M.Wt	537.63
Formula	C30H34F3N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-((1s,3R)-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl)phenyl)-6-(((S)-3-methylpiperidin-1-yl)methyl)-4-(trifluoromethyl)isoindolin-1-one

1. Serah W Kimani, et al. Commun Biol. 2023 Dec 16;6(1):1272.