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CAY10526

Chemical Structure : CAY10526

CAS No.: 938069-71-7

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CAY10526 (CAY-10526)

Catalog No.: PC-38615Not For Human Use, Lab Use Only.

CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression, dose-dependently inhibits PGE2 production in LPS-stimulated RAW 264.7 cells with IC50 of 1.8 uM.

Physicochemical Properties

M.Wt 311.15
Formula C12H7BrO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-Benzo[b]thien-2-yl-3-bromo-5-hydroxy-2(5H)-furanone

References

1. Claveau, D., et al. J. Immunol. 170, 4738-4744 (2003).

2. Guay, J., et al. J. Biol. Chem. 279(23), 24866-24872 (2004).

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