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CB-618

Chemical Structure : CB-618

CAS No.: 1463520-70-8

CB-618 (CB 618;CB 238618)

Catalog No.: PC-61942Not For Human Use, Lab Use Only.

CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.

Physicochemical Properties

M.Wt 290.25
Formula C8H10N4O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Sulfuric acid,mono[(1R,2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester

References

1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6.

2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17.

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