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CB-618 sodium

Chemical Structure : CB-618 sodium

CAS No.: 1628207-16-8

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CB-618 sodium (CB618, CB 238618)

Catalog No.: PC-61943Not For Human Use, Lab Use Only.

CB-618 sodium (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CB-618 sodium (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.
    CB-618 displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.

    Physicochemical Properties

    M.Wt 312.23
    Formula C8H10N4O6S.Na
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1R,2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate, sodium salt

    References

    1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6.

    2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17.

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