CBR64

Chemical Structure : CBR64

Catalog No.: PC-26175Not For Human Use, Lab Use Only.

CBR64 is a specific small molecule bacterial RNA polymerase (RNAP) inhibitor, inhibits catalytic activities of RNAP but not translocation of RNA or DNA, inhibits nucleotide addition.

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Biological Activity

CBR64 is a specific small molecule bacterial RNA polymerase (RNAP) inhibitor, inhibits catalytic activities of RNAP but not translocation of RNA or DNA, inhibits nucleotide addition.

Physicochemical Properties

M.Wt	349.13
Formula	C14H9Cl2F3N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Chloro-N-(3-chlorophenyl)-N′-hydroxy-3-(trifluoromethyl)benzenecarboximidamide

References

1. Artsimovitch I, et al. A new class of bacterial RNA polymerase inhibitor affects nucleotide addition. Science. 2003 Oct 24;302(5645):650-4.

2. Villain-Guillot P, et al. Antimicrob Agents Chemother. 2007 Sep;51(9):3117-21.

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CBR64

Biological Activity

Physicochemical Properties

References

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