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Chemical Structure : CCF0058981
CAS No.: 2708934-53-4
Catalog No.: PC-72198Not For Human Use, Lab Use Only.
CCF0058981 (CCF981) is a potent, selective, noncovalent inhibitor of the SARS-CoV-1/SARS-CoV-2 3CL protease (3CLpro) with IC50 of 19 and 68 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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CCF0058981 (CCF981) is a potent, selective, noncovalent inhibitor of the SARS-CoV-1/SARS-CoV-2 3CL protease (3CLpro) with IC50 of 19 and 68 nM, respectively.
CCF0058981 (CCF981) demonstrated antiviral efficacy against infectious SARS-CoV-2 virus in Vero E6 cells with EC50 of 0.497 and 0.558 uM in CPE inhibition assay and plaque reduction assay, respectively, with CC50>50 uM, which is comparable in potency to remdesivir.
| M.Wt | 442.907 | |
| Formula | C24H19ClN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(4-(1H-Imidazol-5-yl)phenyl)-2-(1H-benzo[d][1,2,3]triazol-1-yl)-N-(3-chlorobenzyl)acetamide |
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1. Sang Hoon Han, et al. J Med Chem. 2021 Aug 4;acs.jmedchem.1c00598.
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