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Chemical Structure : CCR10 antagonist 1
Catalog No.: PC-35029Not For Human Use, Lab Use Only.
CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.
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CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.
CCR10 antagonist 1 demonstrates functional CCR1 antagonism by inhibiting the CCL27 dependent chemotaxis of Ba/F3 cells stably transfected with human CCR10 with an IC50 of 53 nM.
CCR10 antagonist 1 exhibits no antagonism of murine CCL27 dependent Ca2+ flux in CHO-K cells stably transfected with murine CCR10 at 20 uM.
| M.Wt | 519.398 | |
| Formula | C19H24Cl2N6O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Abeywardane A, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283.
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