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Chemical Structure : CCX-354
CAS No.: 1010073-75-2
Catalog No.: PC-35832Not For Human Use, Lab Use Only.
CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $478 | In stock | |
| 10 mg | $758 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA).
| M.Wt | 451.915 | |
| Formula | C22H22ClN7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-1-(4-(4-chloro-3-methoxyphenyl)piperazin-1-yl)ethan-1-one |
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1. Tak PP, et al. Ann Rheum Dis. 2013 Mar;72(3):337-44.
2. Harcken C, et al. Bioorg Med Chem Lett. 2018 Nov 9. pii: S0960-894X(18)30880-1.
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