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Chemical Structure : CDE 096
Catalog No.: PC-70342Not For Human Use, Lab Use Only.
CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively).
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CDE 096 (CDE-096, CDE096) is a selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively); shows ineffective against two closely related serpins, antithrombin and α1-PI; blocks PAI-1 binding to vitronectin with IC50 of 22 nM.
| M.Wt | 583.425 | |
| Formula | C25H20F3NO12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li SH, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4941-9.
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