Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CDPPB
Catalog No.: PC-62955Not For Human Use, Lab Use Only.
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively; reverses amphetamine-induced locomotor activity and amphetamine-induced deficits in prepulse inhibition in rats.
| M.Wt | 364.408 | |
| Formula | C23H16N4O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Kinney GG, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):199-206.
2. Chen Y, et al. Mol Pharmacol. 2007 May;71(5):1389-98.
3. Lindsley CW, et al. J Med Chem. 2004 Nov 18;47(24):5825-8.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
