CGDF-190-20

Chemical Structure : CGDF-190-20

Catalog No.: PC-20245Not For Human Use, Lab Use Only.

CGDF-190-20 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 365 nM in FP assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CGDF-190-20 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 365 nM in FP assays.

M.Wt	367.42
Formula	C19H17N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((E)-(((Z)-4-cyclopropyl-2-(phenylimino)thiazol-3(2H)-yl)imino)methyl)benzene-1,2,3-triol

1. L.D. Walensky, Inhibition of mcl-1 and/or bfl-1/a1, in: U.S. Pat. Appl. Publ., Dana-Farber Cancer Institute, Inc., USA, 2015.