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Chemical Structure : CGP-53716
Catalog No.: PC-70043Not For Human Use, Lab Use Only.
A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells.
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A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells; shows selectivity for inhibition of PDGF-mediated events such as PPDGFR autophosphorylation, cellular tyrosine phosphorylation, and c-Fos mRNA induction in response to PDGF stimulation of intact cells.
| M.Wt | 381.439 | |
| Formula | C23H19N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Buchdunger E, et al. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2558-62.
2. Major TC, et al. J Pharmacol Exp Ther. 1997 Oct;283(1):402-10.
3. Mayer AM, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):633-44.
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