You are here:Home-Chemical Inhibitors & Agonists-TGF-beta/Smad-PKC-CGP60474
CGP60474

Chemical Structure : CGP60474

CAS No.: 164658-13-3

CGP60474 (CGP-60474;CGP 60474)

Catalog No.: PC-42784Not For Human Use, Lab Use Only.

A potent CDK1 inhibitor with IC50 of 17 nM.

Packing Price Stock Quantity
10 mg $112 In stock
50 mg $400 In stock
100 mg $665.6 In stock

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent CDK1 inhibitor with IC50 of 17 nM; exhibits lower potency at CDK2 (IC50=50-80nM) and moderate potency at CDK4 (IC50=700 nM).

Physicochemical Properties

M.Wt 355.8214
Formula C18H18ClN5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-

References

1. Ruetz S, et al. Curr Med Chem Anticancer Agents. 2003 Jan;3(1):1-14.

2. Kuo GH, et al. J Med Chem. 2005 Jul 14;48(14):4535-46.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: