CHF-6333 | Neutrophil elastase inhibitor

Chemical Structure : CHF-6333

Catalog No.: PC-25805Not For Human Use, Lab Use Only.

CHF-6333 is is a potent, selective neutrophil elastase (NE) inhibitor with IC50 of 0.22 nM for human neutrophil elastase (HNE).

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

CHF-6333 is is a potent, selective neutrophil elastase (NE) inhibitor with IC50 of 0.22 nM for human neutrophil elastase (HNE).

M.Wt	621.46
Formula	C27H28BrF3N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-{5-Cyano-2-[(R)-6-methoxycarbonyl-7-methyl-3-oxo-8-(3-trifluoromethyl-phenyl)-2,3,5,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidin-5-yl]-phenyl}-ethyl)-trimethylammonium bromide

1. Armani E, et al. J Med Chem. 2025 Nov 27. doi: 10.1021/acs.jmedchem.5c02638.