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Chemical Structure : CK-2-63
Catalog No.: PC-49602Not For Human Use, Lab Use Only.
CK-2-63 is a potent first-in-class M. tuberculosis cytochrome bd (cyt bd) inhibitor, demonstrates growth suppression of M. tuberculosis H37Rv with IC50 of 3.7 uM.
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CK-2-63 is a potent first-in-class M. tuberculosis cytochrome bd (cyt bd) inhibitor, demonstrates growth suppression of M. tuberculosis H37Rv with IC50 of 3.7 uM.
CK-2-63 potentiate and synergize the growth inhibition and bactericidal activity of known electron transport chain (ETC) inhibitors including Q203 and BDQ.
| M.Wt | 411.38 | |
| Formula | C23H16F3NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Laura N Jeffreys, et al. ACS Infect Dis. 2023 Jan 6. doi: 10.1021/acsinfecdis.2c00283.
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