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Chemical Structure : CMPD167
Catalog No.: PC-61964Not For Human Use, Lab Use Only.
CMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association, inhibits different stages of the virus-cell attachment and entry process (CCR5-using virus SHIV-162P3, IC50<1 nM)..
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CMPD167 (MRK-1) is an orally acitve small molecule that binds to CCR5 to inhibit gp120 association, inhibits different stages of the virus-cell attachment and entry process (CCR5-using virus SHIV-162P3, IC50<1 nM).
| M.Wt | 574.785 | |
| Formula | C35H47FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Veazey RS, et al. Nature. 2005 Nov 3;438(7064):99-102.
2. Veazey RS, et al. Nat Med. 2005 Dec;11(12):1293-4.
3. Ketas TJ, et al. Virology. 2007 Aug 1;364(2):431-40.
4. Malcolm RK, et al. Antimicrob Agents Chemother. 2012 May;56(5):2251-8.
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