 
                Chemical Structure : CPTH2
CAS No.: 357649-93-5
Catalog No.: PC-35322Not For Human Use, Lab Use Only.
CPTH2 is a specific histone acetyltransferase inhibitor modulating Gcn5 network in vitro and in vivo, inhibits H3 acetylation and induces cell-cycle perturbation and apoptosis in U-937 cells.
| Packing | Price | Stock | Quantity | 
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote | 
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
	CPTH2 is a specific histone acetyltransferase inhibitor modulating Gcn5 network in vitro and in vivo, inhibits H3 acetylation and induces cell-cycle perturbation and apoptosis in U-937 cells.
	CPTH2 increases E1A CR3 transactivation of human adenovirus through inhibition of HAT GCN5.
	CPTH2 also reduces virus yield during infection.
	CPTH2 induces apoptosis and decreases the invasiveness of a ccRCC cell line through the inhibition of KAT3B.
| M.Wt | 291.797 | |
| Formula | C14H14ClN3S | |
| Appearance | Solid | |
| Storage | 
 | 
 | 
| Solubility | 10 mM in DMSO | |
| Chemical Name/SMILES | N-[4-(4-Chloro-phenyl)-thiazol-2-yl]-N'-cyclopentylidene-hydrazine | |
1. Chimenti F, et al. J Med Chem. 2009 Jan 22;52(2):530-6.
2. Trisciuoglio D, et al. Clin Cancer Res. 2012 Jan 15;18(2):475-86.
3. Cocco E, et al. Clin Epigenetics. 2018 Apr 4;10:44.
4. Ablack JN, et al. J Virol. 2012 Aug;86(15):8198-209.

 
                 
                 
                 
                 
                 
                 
                 
                 
            
            
        Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright