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CRN02481

Chemical Structure : CRN02481

CAS No.: 2374259-11-5

CRN02481 (CRN 02481)

Catalog No.: PC-38746Not For Human Use, Lab Use Only.

CRN02481 is a potent and selective SST5 receptor agonist with EC50 of 0.37 nM (human SST5), with excellent selectivity against SST1, SST2, SST3 and SST4 receptors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CRN02481 is a potent and selective SST5 receptor agonist with EC50 of 0.37 nM (human SST5), with excellent selectivity against SST1, SST2, SST3 and SST4 receptors.

Physicochemical Properties

M.Wt 412.472
Formula C24H21FN6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-(4-(3-aminopyrrolidin-1-yl)-5-(4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)-5-fluorobenzonitrile \

References

1. Jian Zhao, et al. Bioorg Med Chem Lett. 2022 May 20;128807.

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