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CTAP

Chemical Structure : CTAP

CAS No.: 103429-32-9

CTAP

Catalog No.: PC-27170Not For Human Use, Lab Use Only.

CTAP is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CTAP is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors.

Physicochemical Properties

M.Wt 1104.30
Formula C51H69N13O11S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{d-Phe}-Cys-Tyr-{d-Trp}-Arg-Thr-{Pen}-Thr-NH2 (Disulfide bridge:Cys2-Pen7)

References

1. Abbruscato TJ, et al. J Pharmacol Exp Ther. 1997 Jan;280(1):402-9.

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