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CTPB

Chemical Structure : CTPB

CAS No.: 586976-24-1

CTPB (p300 activator CTPB)

Catalog No.: PC-62266Not For Human Use, Lab Use Only.

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B), which enhanced HAT-dependent transcriptional activation.

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Biological Activity

CTPB is an anacardic acid derivative, was reported as a selective activator of p300 (KAT3B) HAT activity but not PCAF (KAT2B), which enhanced HAT-dependent transcriptional activation.
CTPB has no effect on histone deacetylase activity.
CTPB promotes the survival and neurite growth of the SH-SY5Y cells, and also protects these cells from cell death induced by the neurotoxin 6-hydroxydopamine.

Physicochemical Properties

M.Wt 554.135
Formula C31H43ClF3NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide

References

1. Balasubramanyam K, et al. J Biol Chem. 2003 May 23;278(21):19134-40.

2. Hegarty SV, et al. Neurotox Res. 2016 Oct;30(3):510-20.

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