Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CYM5442
CAS No.: 1094042-01-9
Catalog No.: PC-63009Not For Human Use, Lab Use Only.
CYM 5442 is a potent and selective S1P1 agonist with EC50 of 1.35 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $138 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CYM 5442 is a potent and selective S1P1 agonist with EC50 of 1.35 nM.
CYM5442 activates S1P1-dependent p42/p44 MAPK phosphorylation and induces S1P1-dependent blood lymphopenia, decreasing B lymphocytes by 65% and T lymphocytes by 85% of vehicle.
| M.Wt | 445.944 | |
| Formula | C23H28ClN3O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride |
|
1. Gonzalez-Cabrera PJ, et al. Mol Pharmacol. 2008 Nov;74(5):1308-18.
2. Gonzalez-Cabrera PJ, et al. Mol Pharmacol. 2012 Feb;81(2):166-74.
3. Cheng Q, et al. Cell Mol Immunol. 2015 Nov;12(6):681-91.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
