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CZC-8004

Chemical Structure : CZC-8004

CAS No.: 916603-07-1

CZC-8004 (CZC 8004;CZC8004;Dianilinopyrimidine-01)

Catalog No.: PC-60538Not For Human Use, Lab Use Only.

CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CZC-8004 (CZC8004, Dianilinopyrimidine-01) is a pan-specific kinase inhibitor that binds to a broad range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES at low micromolar concentrations.

    Physicochemical Properties

    M.Wt 309.3
    Formula C17H16FN5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N2-​[4-​(aminomethyl)​phenyl]​-​5-​fluoro-​N4-​phenyl-2,​4-​pyrimidinediamine

    References

    1. Klutchko SR, et al. J Med Chem. 1998 Aug 13;41(17):3276-92.

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