CZS-089 | PLK4 inhibitor | Probechem Biochemicals

Chemical Structure : CZS-089

Catalog No.: PC-25891Not For Human Use, Lab Use Only.

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

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Biological Activity

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

M.Wt	503.51
Formula	C24H18FN7O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea

1. Yin Sun, et al. J Med Chem. 2023 Feb 23;66(4):2396-2421.