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Calcitriol

Chemical Structure : Calcitriol

CAS No.: 32222-06-3

Calcitriol (1,25-Dihydroxyvitamin D3)

Catalog No.: PC-42034Not For Human Use, Lab Use Only.

Calcitriol (1,25-Dihydroxyvitamin D3) is a hormonally active metabolite of vitamin D that binds to vitamin D receptor (VDR), a VDR agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Calcitriol (1,25-Dihydroxyvitamin D3) is a hormonally active metabolite of vitamin D that binds to vitamin D receptor (VDR), a VDR agonist.
Calcitriol (1,25-Dihydroxyvitamin D3) increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood, increasing reabsorption of calcium by the kidneys.

Physicochemical Properties

M.Wt 416.6365
Formula C27H44O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-

References

1. Barsony J, et al. Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1436-40. 2. Menaa C, et al. J Bone Miner Res. 2000 Feb;15(2):228-36.

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