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Chemical Structure : Calicheamicin
CAS No.: 108212-75-5
Catalog No.: PC-45655Not For Human Use, Lab Use Only.
Calicheamicin γ1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $680 | In stock | |
| 10 mg | $1200 | In stock |
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Calicheamicin γ1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission; ADC payload used in development of antibody drug conjugates.
| M.Wt | 1368.348 | |
| Formula | C55H74IN3O21S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Carbamic acid, N-[(1R,4Z,8S,13E)-8-[[4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyranosyl]oxy]amino]-2-O-[2,4-dideoxy-4-(ethylamino)-3-O-methyl-α-L-threo-pento |
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1. Lambert JM, et al. Adv Ther. 2017 May;34(5):1015-1035.
2. Guffroy M, et al. Clin Cancer Res. 2017 Apr 1;23(7):1760-1770.
3. Damelin M, et al. Clin Cancer Res. 2015 Sep 15;21(18):4165-73.
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