Camrelizumab |CAS:1798286-48-2 Probechem Biochemicals

Chemical Structure : Camrelizumab

CAS No.:

Camrelizumab (Anti-huamn PD1 mAb, human IgG4 (S228P)-Kappa; SHR-1210)

Catalog No.: PC-Ab1118Not For Human Use, Lab Use Only.

Camrelizumab (HR 301210, INCSHR 1210, SHR 1210) is a humanised high-affinity IgG4-kappa monoclonal antibody that targets the programmed cell death protein 1 (PD-1), binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab blocks the binding of PD-1, expressed on activated T lymphocytes, B cells and natural killer (NK) cells, to its ligands programmed cell death ligand 1 (PD-L1), overexpressed on certain cancer cells, and p

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Biological Activity

Physicochemical Properties

M.Wt
Formula	Human IgG4 (S228P)-Kappa
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Camrelizumab (Anti-huamn PD1 mAb, human IgG4 (S228P)-Kappa; SHR-1210)

Biological Activity

Physicochemical Properties

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